DOD Chronic Pain Management Research Program Funding Opportunities for FY21

June 17, 2021Posted in: Research

https://cdmrp.army.mil/funding/cpmrp

The FY21 Defense Appropriations Act provides funding to the Department of Defense Chronic Pain Management Research Program (CPMRP) to support research of exceptional scientific merit with the potential to make a significant impact on improving the health and quality of life of Service members, Veterans, and all Americans living with chronic pain. Per the FY19 CPMRP Congressional appropriation, chronic pain is defined as a pain that occurs on at least half the days for six months or more, and which can be caused by issues including, but not limited to: combat- and training-related physical or mental stress and trauma, migraines and chronic headaches, traumatic brain injury, arthritis, muscular-skeletal conditions, neurological disease, tick and vector-borne disease, other insect-transmitted or tropical disease, and cancer. The CPMRP seeks to support and promote innovative, high-impact research to prevent the development and improve the management of chronic pain, with specific emphasis on the utilization and implementation of non-opioid therapies or non-addictive complementary methods. The managing agent for the anticipated program announcements/funding opportunities is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Development Command (USAMRDC).

The FY21 CPMRP program announcements and General Application Instructions for the following award mechanisms are posted on the Grants.gov website.

Applications submitted to the FY21 CPMRP must address one or more of the following focus areas:

  • Clinical Exploration Award
    • Chronification of pain (i.e., the acute-to-chronic pain transition)
    • Effectiveness or observational studies of novel techniques/approaches/pathways to chronic pain management
  • Investigator Initiated Research Award
    • Chronification of pain (i.e., the acute-to-chronic pain transition)
    • Development of non-opioid therapies and methods for the treatment of chronic pain
    • Effectiveness or observational studies of novel or untested techniques/approaches/pathways to chronic pain management
  • Translational Research Award
    • Comparative effectiveness studies (for evidence-based, efficacious interventions to manage or prevent chronic pain)
    • Implementation science (for evidence-based, efficacious interventions to manage or prevent chronic pain)
    • Observational studies

https://cdmrp.army.mil/funding/cpmrp

Clinical Exploration Award (new for FY21) – Preproposal due to the Office of Sponsored Research and Programs by July 23. OSRP will submit by the sponsor deadline of July 30, 2021.

Independent Investigators at all levels

Supports proof-of-principle pilot studies, clinical trials, and correlative studies with the potential to resolve current clinical barriers.

  • Research must address one or both of the FY21 CPMRP CEA Focus Areas of chronification of pain and effectiveness or observational studies of novel or untested techniques/approaches/pathways to chronic pain management.
  • Preliminary data are not required for FY21 CPMRP CEA applications.
  • Statistically underpowered studies of efficacy are not pilot studies and will not be supported under the FY21 CPMRP CEA mechanism.
  • Pre-application submission is required; application submission is by invitation only.
  • The maximum allowable funding for the entire period of performance is $250,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is two years.

Investigator-Initiated Research Award – Preproposal Preproposal due to the Office of Sponsored Research and Programs by July 23. OSRP will submit by the sponsor deadline of July 30, 2021.

Investigators at or above the level of Assistant Professor (or equivalent)

Supports innovative research that will make an original and important contribution to the field of research, patient care, and/or quality of life.

  • Research must address one or more of the FY21 CPMRP IIRA Focus Areas of chronification of pain, development of non-opioid therapies and methods for the treatment of chronic pain, and effectiveness or observational studies of novel or untested techniques/approaches/pathways to chronic pain management.
  • Partnering PI Option is available.
  • Multidisciplinary collaborations and innovative approaches are encouraged.
  • Clinical trials will not be funded.
  • Pre-application submission is required; application submission is by invitation only.
  • The maximum allowable funding for the entire period of performance is $900,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is four years.

Translational Research Award –Preproposal due to the Office of Sponsored Research and Programs by July 23. OSRP will submit by the sponsor deadline of July 30, 2021.

Investigators at or above the level of Assistant Professor (or equivalent)

Supports translational research that will accelerate the movement of efficacious, evidence-based ideas into clinical applications.

  • Research must address one or more of the FY21 CPMRP TRA Focus Areas of implementation science, comparative effectiveness, and observational studies related to chronic pain.
  • Partnering PI Option is available.
  • Incorporation of biopsychosocial models of assessment and stakeholder engagement are encouraged.
  • Studies seeking to evaluate new therapies or approaches, either pharmacological or non-pharmacological, that have not been previously evaluated in a clinical setting will not be funded.
  • Pre-application submission is required; application submission is by invitation only
  • The maximum allowable funding for the entire period of performance is $1,400,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is four years.

A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

For email notification when program announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the CPMRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).

Contact the Office of Sponsored Research and Programs for assistance with your proposal at osrp@iit.edu.

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