CHBE Seminar by Mo Jiang: Slug-Flow Process Design for Manufacturing Crystals with Improved Uniformity

Photo of Mo Jiang

Join Mo Jiang, assistant professor in the Department of Chemical and Life Science Engineering at Virginia Commonwealth University, for a seminar on ‘Slug-Flow Process Design for Manufacturing Crystals with Improved Uniformity’ online from 3:15 – 4:30 p.m. on Wednesday, March 9.

Join on Zoom: https://iit-edu.zoom.us/j/85393511200?pwd=ZVFWTlA3aGhscnpoNm1MTjVmWUhFQT09

Abstract: The pharmaceutical and battery industries have increased demands for reproducible and efficient green manufacturing of crystal-based products. For many of these products and their active ingredients (e.g., pharmaceutical tablet, or Lithium-ion battery cell), uniformity and consistency in quality across different scales/stages is a must, and a huge challenge for existing batch processes. This talk focuses on the slug-flow crystal generator design, which is a particular form of tubular crystallizer that combines many of the strengths of other crystallizer configurations to provide enhanced quality control. Experimental validation confirms that the proposed modular designs readily applies to multiple chemicals, while suppressing secondary nucleation, attrition, and clogging/fouling—dominant but undesired phenomena that worsen the ability to quality control.

Biography: Mo Jiang is an assistant professor in the Department of Chemical and Life Science Engineering at Virginia Commonwealth University. Mo’s main research interests include to advance mass production of emerging materials with precise control for health and energy applications, and to understand the links between manufacturing process, particle structure, and product performance. The Jiang Group research is currently funded by NSF, the Department of Energy, U.S. Pharmacopeia, and pharmaceutical companies. Mo has been at VCU since 2018. Mo received a Ph.D. in chemical engineering in 2015 at the Massachusetts Institute of Technology (MIT) then became a postdoctoral associate/fellow there. He received a B.S. in biology in 2006 from Tsinghua University and an M.S. in chemical engineering in 2008 from the University of Illinois at Urbana-Champaign. Before joining the Ph.D. program at MIT, he also interned at Boehringer Ingelheim Pharmaceuticals Inc. and Abbott Laboratories (now AbbVie).

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