Department of Defense Duchenne Muscular Dystrophy Research Program

The FY21 Defense Appropriations Act provides funding to the Department of Defense Duchenne Muscular Dystrophy Research Program (DMDRP) to support research addressing Duchenne pathobiology and discovery and development of therapeutics, related devices, and tools. The managing agent for the anticipated program announcements/funding opportunities is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Development Command (USAMRDC).

The FY21 DMDRP program announcements and General Application Instructions for the following award mechanisms are posted on the Grants.gov website.

https://cdmrp.army.mil/funding/dmdrp

Idea Development Award–Your proposal is due to the Office of Sponsored Research no later than five business prior to the sponsor deadline of August 11.

Established Investigators: Independent investigators at or above the level of Assistant Professor (or equivalent);

or

New Investigators: Investigators that meet the following criteria by the application submission deadline date:

Have not previously received a DMDRP Idea Development Award

Are within 10 years of first faculty appointment (or equivalent)

• Supports the development of innovative, high-impact ideas that advance the understanding of Duchenne muscular dystrophy (DMD) and ultimately lead to improved outcomes.

• Must address opportunities and challenges in the development of safe and effective macromolecular and
cellular therapies that address primary pathology of DMD. Eligible therapeutic strategies include: gene
therapy, genome editing, oligonucleotide therapies, exon skipping, protein therapeutics, and cell therapies.

• Therapies that will be efficacious across the life-span, particularly in adolescents and adults are encouraged.

• Preliminary data required.

• Clinical trials or applications including a clinical trial aim are not allowed.

Maximum funding of $350,000 in direct costs (plus indirect costs).

Maximum period of performance is two years.

Translational Research Award–New for FY21–Preproposal due August 11

Investigators at or above the level of Assistant Professor (or equivalent)

• Supports translational studies that have moved beyond the realm of basic research and have the potential
to result in a near-term impact in clinical research or the clinic.

• Research projects investigating therapies that will be efficacious across the life-span, particularly in
adolescents and adults are strongly encouraged.

• Preliminary data required.

• Clinical trials are allowed.

Maximum funding of $1,300,000 in direct costs (plus indirect costs).
Maximum period of performance is three years.

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final program announcements and General Application Instructions available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

Your proposal is due to the Office of Sponsored Research no later than five business prior to the sponsor deadline. Contact osrp@iit.edu with questions.

For email notification when program announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the DMDRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).