FDSN Seminar Series: Interlaboratory Comparison of SARS-CoV2 Molecular Detection Assays

Join the Department of Food Science and Nutrition for this seminar series event featuring guest speaker Kaiping Deng, a biologist and staff fellow at the United States Food and Drug Administration’s Center for Food Safety and Applied Nutrition (FDA/CFSAN) Proficiency Testing Program.

Kaiping Deng – Biologist, Staff Fellow


Thursday, January 27, 2022 – 1:00 PM Central Time

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‪(661) 527-0275 PIN: ‪524 256 573#

Title:  Interlaboratory Comparison of SARS-CoV2 Molecular Detection Assays in Use by U.S. Veterinary Diagnostic Laboratories

Abstract:  The continued search for intermediate hosts and potential reservoirs for SARS-CoV2 makes it clear that animal surveillance is critical in outbreak response and prevention. U.S. veterinary diagnostic laboratories have used the CDC Real-time RT-PCR assays or other national reference laboratory methods to test animal samples. However, these methods have only been evaluated using internal validation protocols. To help the laboratories evaluate their SARS-CoV2 test methods, interlaboratory comparison exercises (ICEs) were collaboratively conducted by the Veterinary Laboratory Investigation and Response Network (Vet-LIRN) in FDA/CVM, Moffett Proficiency Testing Team in FDA/CFSAN and other organizations.  SARS-CoV2 RNA samples were prepared and shipped to participating laboratories. Results were analyzed according to the principles of ISO 16140-2:2016 standard. The results revealed the specificity and sensitivity of the laboratory methods for SARS-CoV2 detection. The laboratory’s ability to detect the emerging variants Alpha (B.1.1.7) and Beta (B.1.351) was also evaluated. Demonstrating that their assays are sensitive and accurate is important to the veterinary laboratory community to ensure reliable diagnosis of SARS-CoV2–infected animals.

Kaiping Deng – Biologist, Staff Fellow


Short bio:

Kaiping Deng is Biologist Staff Fellow at FDA/CFSAN Proficiency Testing (PT) Program.  She received her PhD in Biochemistry and Molecular Biology from Oklahoma State University. Before she joined the PT Program last October, Kaiping was a Senior Scientist/Research Assistant professor at IIT to work on multiple research projects and Sprout Safety Alliance.  She was also involved in teaching the Food Microbiology lecture and lab class.  Kaiping is currently working on multi-lab validation and inter-lab comparison of microbial detection methods.